SCHEMBL9816580

SCHEMBL9816580

CCCCNCCS(=O)(=O)CCO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40
CA12 O43570 1/20 0.40
CA7 P43166 1/20 0.40
CA14 Q9ULX7 1/20 0.40
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
RELA Q04206 4/20 0.37
S1PR2 O95136 5/20 0.36
S1PR4 O95977 5/20 0.36
S1PR1 P21453 5/20 0.36
S1PR3 Q99500 5/20 0.36
S1PR5 Q9H228 1/20 0.36
ADH1B P00325 1/20 0.35
ADH1C P00326 1/20 0.35
ADH1A P07327 1/20 0.35
ADH7 P40394 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9816370 0.94 ALDH1A1 (0.50) TSHRALDH1A1CA1CA2RELA
SCHEMBL9816608 0.92 ALDH1A1 (0.48) TSHRALDH1A1CA1CA2RELA
SCHEMBL9816676 0.92 ALDH1A1 (0.48) TSHRALDH1A1CA1CA2RELA
SCHEMBL9816512 0.92 ALDH1A1 (0.48) TSHRALDH1A1CA1CA2RELA
SCHEMBL9816627 0.92 ALDH1A1 (0.48) TSHRALDH1A1CA1CA2RELA
SCHEMBL9816529 0.92 ALDH1A1 (0.48) TSHRALDH1A1CA1CA2RELA
SCHEMBL9816606 0.88 PAOX (0.36) CA1CA2ADH1BADH1AADH7
SCHEMBL9816532 0.85 APEX1 (0.32)
SCHEMBL9248155 0.85 RELA (0.49) TSHRALDH1A1CA1CA2RELA
SCHEMBL9366515 0.83 TSHR (0.48) TSHRALDH1A1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0174909-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1991-10-16 EP disclosed
US-4841028-A FOR COLD PAD-BATCH PROCESS HUNTSMAN INTERNATIONAL LLC 1989-06-20 US disclosed
US-4709018-A COLORFAST CIBA-GEIGY CORPORATION (US) 1987-11-24 US disclosed
EP-0141776-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-07-08 EP disclosed
EP-0174909-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1986-03-19 EP disclosed