Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427162 | 0.71 | SLC6A2 (0.39) | OPRM1OPRD1OPRK1OPRL1DPP4 | |
| SCHEMBL703009 | 0.69 | POLB (0.41) | CTSKOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL11936252 | 0.69 | SLC6A3 (0.43) | TDP1SLC6A4SLC6A3PKM | |
| SCHEMBL7453749 | 0.69 | POLB (0.44) | OPRM1OPRD1OPRK1OPRL1CASR | |
| SCHEMBL6254117 | 0.67 | POLB (0.42) | OPRM1OPRD1OPRK1OPRL1CASR | |
| SCHEMBL19806000 | 0.67 | SLC6A3 (0.39) | TDP1SLC6A3PKM | |
| Hexane SCHEMBL28169137 | 0.66 | TSHR (0.37) | ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27281580 | 0.66 | CASR (0.46) | OPRM1OPRD1OPRK1OPRL1CASR | |
| SCHEMBL27487946 | 0.66 | POLB (0.45) | CTSKOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL38656448 | 0.66 | ALDH1A1 (0.43) | OPRM1OPRD1OPRK1OPRL1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135714-B1 | SUSTAINED RELEASE COMPOSITIONS FOR BIOLOGICALLY ACTIVE MATERIALS | MELAMINE CHEMICALS, INC. (US) | 1991-11-06 | — | — | EP | disclosed |