Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 7/20 | 0.52 |
| ▸ | INPP5A | Q14642 | 5/20 | 0.52 |
| ▸ | INPP5B | P32019 | 2/20 | 0.52 |
| ▸ | SRC | P12931 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816644 | 0.84 | TSHR (0.42) | HSD17B10KDM4EHPGDALDH1A1TSHR | |
| SCHEMBL8589535 | 0.80 | TSHR (0.38) | INPPL1INPP5AINPP5BSRCHSD17B10 | |
| SCHEMBL2573126 | 0.79 | INPPL1 (0.70) | INPPL1INPP5AINPP5BSRCHSD17B10 | |
| SCHEMBL31117138 | 0.77 | INPPL1 (0.47) | INPPL1INPP5AINPP5BSRCHSD17B10 | |
| SCHEMBL19808 | 0.74 | INPPL1 (0.57) | INPPL1INPP5AINPP5BSRCHSD17B10 | |
| SCHEMBL30770359 | 0.74 | INPPL1 (0.57) | INPPL1INPP5AINPP5BSRCHSD17B10 | |
| SCHEMBL1100136 | 0.74 | INPPL1 (0.57) | INPPL1INPP5AINPP5BSRCHSD17B10 | |
| SCHEMBL7642520 | 0.73 | HSD17B10 (0.46) | INPPL1INPP5AINPP5BSRCHSD17B10 | |
| SCHEMBL9645945 | 0.73 | INPPL1 (0.61) | INPPL1INPP5AINPP5BSRCHSD17B10 | |
| SCHEMBL9351941 | 0.72 | POLB (0.49) | HSD17B10KDM4EHPGDTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135714-B1 | SUSTAINED RELEASE COMPOSITIONS FOR BIOLOGICALLY ACTIVE MATERIALS | MELAMINE CHEMICALS, INC. (US) | 1991-11-06 | — | — | EP | disclosed |