Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816649 | 0.84 | INPPL1 (0.52) | TSHRSMN1; SMN2HSD17B10POLBTDP1 | |
| SCHEMBL8589535 | 0.76 | TSHR (0.38) | TSHRSMN1; SMN2HSD17B10POLBTDP1 | |
| SCHEMBL2774997 | 0.75 | SLC6A2 (0.49) | TSHRSMN1; SMN2HSD17B10POLBTDP1 | |
| SCHEMBL30514820 | 0.73 | CA1 (0.57) | TSHRSMN1; SMN2HSD17B10POLBTDP1 | |
| SCHEMBL25820737 | 0.73 | POLB (0.42) | TSHRSMN1; SMN2HSD17B10POLBTDP1 | |
| SCHEMBL71009 | 0.73 | CA1 (0.57) | TSHRSMN1; SMN2HSD17B10POLBTDP1 | |
| SCHEMBL11779552 | 0.71 | PTGS2 (0.38) | — | |
| SCHEMBL35762 | 0.71 | KDM4E (0.50) | TSHRSMN1; SMN2POLBTDP1MAPT | |
| SCHEMBL19809 | 0.71 | CA1 (0.62) | TSHRSMN1; SMN2HSD17B10POLBTDP1 | |
| SCHEMBL29405980 | 0.71 | KDM4E (0.50) | TSHRSMN1; SMN2POLBTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135714-B1 | SUSTAINED RELEASE COMPOSITIONS FOR BIOLOGICALLY ACTIVE MATERIALS | MELAMINE CHEMICALS, INC. (US) | 1991-11-06 | — | — | EP | disclosed |