Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9466232 | 0.89 | TSHR (0.35) | TSHRTAAR1KCNN4MAPK1CYP2C19 | |
| SCHEMBL10324871 | 0.81 | TAAR1 (0.44) | TSHRTAAR1KCNN4MAPK1CYP2C19 | |
| SCHEMBL825609 | 0.76 | TSHR (0.48) | TSHRTAAR1KCNN4MAPK1CYP2C19 | |
| SCHEMBL30788816 | 0.74 | ALDH1A1 (0.46) | TSHRTAAR1KCNN4MAPK1CYP2C19 | |
| SCHEMBL9466812 | 0.74 | MAPK1 (0.41) | TAAR1KCNN4MAPK1CYP2C19HIF1A | |
| SCHEMBL23781410 | 0.73 | TSHR (0.50) | TSHRTAAR1KCNN4MAPK1CYP2C19 | |
| SCHEMBL28366627 | 0.73 | TSHR (0.50) | TSHRTAAR1KCNN4MAPK1CYP2C19 | |
| SCHEMBL6685341 | 0.73 | TSHR (0.50) | TSHRTAAR1KCNN4MAPK1CYP2C19 | |
| SCHEMBL474982 | 0.72 | TAAR1 (0.50) | TSHRTAAR1KCNN4MAPK1CYP2C19 | |
| SCHEMBL10464795 | 0.71 | TSHR (0.48) | TSHRTAAR1KCNN4MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451679-A2 | Method of producing polymers | NIPPON ZEON CO., LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |