SCHEMBL10324871

SCHEMBL10324871

CCC(c1ccccc1)(C(C)(C)C)C(CC)(c1ccccc1)C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.44
KCNN4 O15554 4/20 0.43
MAPK1 P28482 1/20 0.42
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
ALDH1A1 P00352 3/20 0.39
ALOX15 P16050 1/20 0.39
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
NR3C2 P08235 1/20 0.36
TSHR P16473 2/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9816665 0.81 TSHR (0.44) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL30788816 0.78 ALDH1A1 (0.46) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL9466812 0.78 MAPK1 (0.41) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL18419705 0.77 TAAR1 (0.46) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL15043735 0.76 ALDH1A1 (0.39) TAAR1MAPK1CYP2C19HIF1AALDH1A1
SCHEMBL474982 0.76 TAAR1 (0.50) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL14050234 0.75 TAAR1 (0.44) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL7932124 0.75 TAAR1 (0.44) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL15801006 0.75 TAAR1 (0.44) TAAR1KCNN4MAPK1CYP2C19HIF1A
Tert-Amylbenzene SCHEMBL131593 0.74 TAAR1 (0.61) TAAR1KCNN4MAPK1CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2663594-B1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-26 EP claimed
CN-103415564-B For the anti-oxidant compounds of polyolefin resin DOW GLOBAL TECHNOLOGIES LLC (US) 2016-04-13 CN claimed
EP-2663594-A1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS Dow Global Technologies LLC (US) 2013-11-20 EP claimed
US-20130287985-A1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS DEMIRORS MEHMET (US) 2013-10-31 US claimed
WO-2012096962-A1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-07-19 WO claimed
EP-2663594-B1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-26 EP disclosed
CN-103415564-B For the anti-oxidant compounds of polyolefin resin DOW GLOBAL TECHNOLOGIES LLC (US) 2016-04-13 CN disclosed
EP-2663594-A1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS Dow Global Technologies LLC (US) 2013-11-20 EP disclosed
US-20130287985-A1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS DEMIRORS MEHMET (US) 2013-10-31 US disclosed
WO-2012096962-A1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-07-19 WO disclosed