Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.40 |
| ▸ | ADH1A | P07327 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965411 | 1.00 | ATM (0.54) | ATMRAB9APOLBABCC1KMT2A | |
| SCHEMBL965799 | 0.98 | ATM (0.51) | ATMRAB9APOLBABCC1KMT2A | |
| SCHEMBL969177 | 0.96 | ATM (0.49) | ATMRAB9APOLBABCC1KMT2A | |
| SCHEMBL967284 | 0.89 | — | — | |
| SCHEMBL12745101 | 0.81 | ATM (0.53) | ATMRAB9APOLBABCC1KMT2A | |
| SCHEMBL12385852 | 0.81 | ATM (0.38) | ATMRAB9APOLBABCC1KMT2A | |
| SCHEMBL11209209 | 0.80 | TSHR (0.50) | ATMRAB9AKMT2APHGDHALDH1A1 | |
| SCHEMBL2875858 | 0.80 | ATM (0.40) | ATMRAB9APOLBABCC1KMT2A | |
| SCHEMBL24723356 | 0.79 | PIK3CD (0.40) | ATMRAB9APOLBABCC1KMT2A | |
| SCHEMBL679618 | 0.79 | CCR5 (0.52) | ATMRAB9APOLBABCC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135714-B1 | SUSTAINED RELEASE COMPOSITIONS FOR BIOLOGICALLY ACTIVE MATERIALS | MELAMINE CHEMICALS, INC. (US) | 1991-11-06 | — | — | EP | disclosed |
| US-3962307-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |