Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 2/20 | 0.38 |
| ▸ | ADH1A | P07327 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19027273 | 0.88 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL689399 | 0.84 | TSHR (0.45) | TSHRKDM4EMEN1LMNAALOX15 | |
| SCHEMBL2875858 | 0.82 | ATM (0.40) | TSHRKDM4EKMT2AATMADH1C | |
| SCHEMBL965411 | 0.80 | ATM (0.54) | TSHRMEN1KMT2APHGDHATM | |
| SCHEMBL9816779 | 0.80 | ATM (0.54) | TSHRMEN1KMT2APHGDHATM | |
| SCHEMBL968899 | 0.79 | L3MBTL1 (0.46) | TSHRKDM4EMEN1LMNAKMT2A | |
| SCHEMBL31456097 | 0.78 | TSHR (0.65) | TSHRKDM4EMEN1LMNAALOX15 | |
| SCHEMBL31607256 | 0.78 | SLC6A2 (0.41) | TSHRKDM4ELMNAKMT2AATM | |
| SCHEMBL1869679 | 0.78 | PHGDH (0.48) | TSHRKDM4EMEN1LMNAALOX15 | |
| SCHEMBL965799 | 0.77 | ATM (0.51) | TSHRMEN1KMT2APHGDHATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1364155-A | N-Cyanomethyl amides as protease inhibitors | AXYS PHARM INC (US) | 2002-08-14 | — | — | CN | disclosed |
| EP-0083096-A2 | Production of urethane compounds | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-07-06 | — | — | EP | disclosed |
| US-4240954-A | CYCLOHEXYL UREAS OR THIOUREAS | AMERICAN CYANAMID COMPANY (US) | 1980-12-23 | — | — | US | disclosed |