SCHEMBL9816840

SCHEMBL9816840

CCCCN(CCCC)C(=S)OCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
CCR6 P51684 1/20 0.43
PAX8 Q06710 1/20 0.43
DRD2 P14416 1/20 0.42
OPRM1 P35372 1/20 0.42
DRD3 P35462 1/20 0.42
OPRD1 P41143 1/20 0.42
OPRK1 P41145 1/20 0.42
CETP P11597 3/20 0.41
KCNH2 Q12809 1/20 0.41
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27509628 0.90 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL17764211 0.86 ALDH1A1 (0.46) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL9099866 0.83 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL14476880 0.81 CCR6 (0.63) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL1254822 0.79 ALDH1A1 (0.49) ALDH1A1MAPK1TDP1L3MBTL1CA12
SCHEMBL18057682 0.78 CCR6 (0.60) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL25628629 0.78 CCR6 (0.64) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL9942494 0.78 CCR6 (0.57) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL27343331 0.77 CCR6 (0.56) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL9870771 0.77 MAPT (0.48) ALDH1A1CYP3A4GAAHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0135714-B1 SUSTAINED RELEASE COMPOSITIONS FOR BIOLOGICALLY ACTIVE MATERIALS MELAMINE CHEMICALS, INC. (US) 1991-11-06 EP disclosed
US-3930838-A S-BENZYL-N,N-DISEC-BUTYLTHIOCARBAMATE AND ITS USE AS A RICE FIELD HERBICIDE AND A RICE GROWTH STIMULANT MONTECATINI EDISON S.P.A. (IT) 1976-01-06 US disclosed