Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725706 | 0.89 | LMNA (0.44) | MAPTLMNAHTTGAAALDH1A1 | |
| SCHEMBL2462796 | 0.82 | GRIN2D (0.50) | MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL5299287 | 0.77 | GRIN2D (0.47) | MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL22450141 | 0.77 | MEN1 (0.61) | MAPTLMNAGAAHPGDALDH1A1 | |
| SCHEMBL9816840 | 0.77 | ALDH1A1 (0.47) | MAPTLMNAGAAHPGDALDH1A1 | |
| Ethane SCHEMBL27729139 | 0.76 | GRIN2D (0.46) | MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL31504001 | 0.74 | LMNA (0.50) | MAPTLMNAGAAHPGDKMT2A | |
| SCHEMBL3483514 | 0.74 | LMNA (0.50) | MAPTLMNAGAAHPGDKMT2A | |
| SCHEMBL6754891 | 0.73 | MEN1 (0.51) | MAPTLMNAKMT2AZDHHC2 | |
| SCHEMBL25586470 | 0.73 | MAPT (0.45) | MAPTHTTGAALTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |