Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816929 | 1.00 | ATM (0.53) | ATMLMNAPTPN1DRD1LDHA | |
| SCHEMBL9816930 | 0.88 | DRD1 (0.54) | ATMLMNAPTPN1DRD1ALDH1A1 | |
| SCHEMBL9816924 | 0.88 | DRD1 (0.54) | ATMLMNAPTPN1DRD1ALDH1A1 | |
| SCHEMBL2516037 | 0.86 | LDHA (0.66) | ATMLMNALDHAFPR2MEN1 | |
| SCHEMBL2516039 | 0.86 | LDHA (0.66) | ATMLMNALDHAFPR2MEN1 | |
| SCHEMBL3419160 | 0.86 | LDHA (0.66) | ATMLMNALDHAFPR2MEN1 | |
| Water SCHEMBL9352790 | 0.85 | LDHA (0.64) | ATMLMNALDHAFPR2MEN1 | |
| SCHEMBL8836882 | 0.82 | GNPAT (0.61) | PTPN1MMEBACE1 | |
| Alanine SCHEMBL18301528 | 0.81 | LDHA (0.58) | ATMLDHAFPR2MEN1KMT2A | |
| Alanine SCHEMBL18301527 | 0.81 | LDHA (0.58) | ATMLDHAFPR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106335-B1 | PHARMACEUTICAL COMPOSITION AND A METHOD FOR ENHANCING THE ABSORPTION OF A PHARMACEUTICALLY ACTIVE COMPOUND | Tanabe Seiyaku Co., Ltd. (JP) | 1991-10-23 | — | — | EP | disclosed |