Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816930 | 1.00 | DRD1 (0.54) | DRD1PTPN1LMNAATMBACE1 | |
| SCHEMBL9816922 | 0.88 | ATM (0.53) | DRD1PTPN1LMNAATMBACE1 | |
| SCHEMBL9816929 | 0.88 | ATM (0.53) | DRD1PTPN1LMNAATMBACE1 | |
| SCHEMBL7290024 | 0.87 | ITGB3 (0.51) | LMNAITGB3ITGA2BALDH1A1NPSR1 | |
| SCHEMBL7290022 | 0.87 | ITGB3 (0.51) | LMNAITGB3ITGA2BALDH1A1NPSR1 | |
| SCHEMBL9816890 | 0.83 | MME (0.44) | PTPN1ITGB3ITGA2B | |
| SCHEMBL9816898 | 0.83 | MME (0.44) | PTPN1ITGB3ITGA2B | |
| SCHEMBL11457694 | 0.81 | MEN1 (0.50) | PTPN1ITGB3ITGA2B | |
| SCHEMBL8836882 | 0.80 | GNPAT (0.61) | PTPN1BACE1LTA4HGNPATBACE2 | |
| SCHEMBL11458383 | 0.79 | PTPN1 (0.49) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106335-B1 | PHARMACEUTICAL COMPOSITION AND A METHOD FOR ENHANCING THE ABSORPTION OF A PHARMACEUTICALLY ACTIVE COMPOUND | Tanabe Seiyaku Co., Ltd. (JP) | 1991-10-23 | — | — | EP | claimed |
| EP-0106335-A2 | Pharmaceutical composition and a method for enhancing the absorption of a pharmaceutically active compound | Tanabe Seiyaku Co., Ltd. (JP) | 1984-04-25 | — | — | EP | claimed |
| EP-0106335-B1 | PHARMACEUTICAL COMPOSITION AND A METHOD FOR ENHANCING THE ABSORPTION OF A PHARMACEUTICALLY ACTIVE COMPOUND | Tanabe Seiyaku Co., Ltd. (JP) | 1991-10-23 | — | — | EP | disclosed |
| EP-0106335-A2 | Pharmaceutical composition and a method for enhancing the absorption of a pharmaceutically active compound | Tanabe Seiyaku Co., Ltd. (JP) | 1984-04-25 | — | — | EP | disclosed |
| US-4228183-A | HYPOTENSIVE AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |
| EP-0007441-A1 | N - (N-Acetyl-L-methionyl) - 3,4 -diethoxy-carbonyloxy-phenethylamine, process for preparing same and a pharmaceutical composition containing said compound. | Tanabe Seiyaku Co., Ltd. (JP) | 1980-02-06 | — | — | EP | disclosed |