SCHEMBL9817009

SCHEMBL9817009

CCC(c1ccc(O)c(-c2ccccc2)c1)(c1ccc(O)c(-c2ccccc2)c1)c1ccc(C)cc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.39
ESR2 Q92731 6/20 0.39
AR P10275 3/20 0.39
CNR1 P21554 2/20 0.39
CNR2 P34972 2/20 0.39
PIM1 P11309 2/20 0.38
BACE1 P56817 3/20 0.38
TP53 P04637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9816986 0.90 ESR1 (0.41) ESR1ESR2ARCNR1CNR2
SCHEMBL9816988 0.88 ESR1 (0.41) ESR1ESR2ARCNR1CNR2
SCHEMBL9817026 0.88 ESR1 (0.44) ESR1ESR2ARCNR1CNR2
SCHEMBL9817002 0.87 CNR1 (0.44) ESR1ESR2ARCNR1CNR2
SCHEMBL9816990 0.85 KIF11 (0.43) ESR1ESR2ARCNR1CNR2
SCHEMBL9817049 0.84 BACE1 (0.42) ESR1ESR2CNR1CNR2PIM1
SCHEMBL9816998 0.83 ESR2 (0.49) ESR1ESR2CNR1CNR2PIM1
SCHEMBL9817004 0.82 ESR1 (0.39) ESR1ESR2ARCNR1CNR2
SCHEMBL2859474 0.81 BACE1 (0.47) ESR1ESR2ARCNR1CNR2
SCHEMBL9817105 0.78 ESR1 (0.44) ESR1ESR2ARCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277627-B1 POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-10-23 EP disclosed
US-4801679-A Polyformal resin and process for producing said resin IDEMITSU KOSAN CO., LTD. (JP) 1989-01-31 US disclosed
EP-0277627-A1 Polyformal resins and process for producing said resins IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-08-10 EP disclosed