SCHEMBL2859474

SCHEMBL2859474

CCC(c1ccccc1)(c1ccc(O)c(-c2ccccc2)c1)c1ccc(O)c(-c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.47
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ESR1 P03372 6/20 0.40
ESR2 Q92731 4/20 0.40
PELI1 Q96FA3 1/20 0.40
AR P10275 1/20 0.40
CNR1 P21554 2/20 0.39
CNR2 P34972 2/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
ALOX5 P09917 2/20 0.38
KIF11 P52732 1/20 0.37
PTPN5 P54829 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9816990 0.92 KIF11 (0.43) BACE1ALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL9713890 0.89 BACE1 (0.48) BACE1CNR1CNR2KIF11
SCHEMBL9713495 0.89 NPC1 (0.40) BACE1PELI1
SCHEMBL2867989 0.88 BACE1 (0.44) BACE1ALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL9817006 0.87 LMNA (0.44) BACE1ALDH1A1HPGDESR1CNR1
SCHEMBL9816992 0.85 HDAC8 (0.41) BACE1ALDH1A1
SCHEMBL9816991 0.85 ESR1 (0.45) BACE1ESR1ESR2CNR1CNR2
SCHEMBL9177536 0.85 ESR1 (0.56) BACE1ALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL9816988 0.84 ESR1 (0.41) BACE1ALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL9817028 0.84 KIF11 (0.44) BACE1ESR1ESR2CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed
EP-0277627-B1 POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-10-23 EP disclosed
US-4801679-A Polyformal resin and process for producing said resin IDEMITSU KOSAN CO., LTD. (JP) 1989-01-31 US disclosed
EP-0277627-A1 Polyformal resins and process for producing said resins IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-08-10 EP disclosed