Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.47 |
| ▸ | CNR2 | P34972 | 15/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | PRKX | P51817 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956568 | 0.99 | CNR1 (0.49) | CNR1CNR2ESR1ESR2BACE1 | |
| SCHEMBL9816981 | 0.96 | ESR1 (0.46) | CNR1CNR2ESR1ESR2BACE1 | |
| SCHEMBL9817011 | 0.90 | BACE1 (0.46) | CNR1CNR2ESR1ESR2BACE1 | |
| SCHEMBL5652317 | 0.89 | CNR1 (0.60) | CNR1CNR2 | |
| SCHEMBL9817033 | 0.88 | ESR1 (0.55) | CNR1CNR2ESR1ESR2BACE1 | |
| SCHEMBL9817080 | 0.87 | ESR1 (0.58) | CNR1CNR2ESR1ESR2BACE1 | |
| SCHEMBL9817147 | 0.86 | ESR1 (0.53) | CNR1CNR2ESR1ESR2 | |
| SCHEMBL9817008 | 0.86 | ESR1 (0.49) | CNR1CNR2ESR1ESR2BACE1 | |
| SCHEMBL9817028 | 0.84 | KIF11 (0.44) | CNR1CNR2ESR1ESR2BACE1 | |
| SCHEMBL19902034 | 0.84 | CNR1 (0.54) | CNR1CNR2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277627-B1 | POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-10-23 | — | — | EP | disclosed |
| US-4801679-A | Polyformal resin and process for producing said resin | IDEMITSU KOSAN CO., LTD. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0277627-A1 | Polyformal resins and process for producing said resins | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |