Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | IAPP | P10997 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817288 | 0.85 | AKR1B1 (0.47) | TAAR1AKR1B1TYRHSPA5IDO1 | |
| SCHEMBL9817336 | 0.81 | HIF1A (0.41) | AKR1B1MEN1POLBMAPTKMT2A | |
| SCHEMBL9817322 | 0.77 | CTSB (0.41) | MEN1KMT2ATDP1 | |
| SCHEMBL30410323 | 0.77 | TSHR (0.49) | CYP4F2CYP4A11NPC1PKMRAB9A | |
| SCHEMBL14360117 | 0.77 | TSHR (0.49) | CYP4F2CYP4A11NPC1PKMRAB9A | |
| SCHEMBL9817390 | 0.77 | ESR1 (0.40) | CYP4F2CYP4A11MEN1POLBMAPT | |
| SCHEMBL9817228 | 0.74 | HPGD (0.46) | NPC1RAB9AMAPT | |
| SCHEMBL28613245 | 0.74 | CYP4F2 (0.48) | CYP4F2CYP4A11NPC1PKMRAB9A | |
| SCHEMBL29852765 | 0.72 | NPC1 (0.52) | CYP4F2CYP4A11NPC1PKMRAB9A | |
| SCHEMBL607310 | 0.72 | NPC1 (0.52) | CYP4F2CYP4A11NPC1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248213-B1 | HYDROXYPHENYL- AND HYDROXYPHENOXYALKANOIC ACID IODOPROPARGYL ESTERS | THE DOW CHEMICAL COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-4731466-A | FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0248213-A2 | Hydroxyphenyl- and hydroxyphenoxyalkanoic acid iodopropargyl esters | THE DOW CHEMICAL COMPANY (US) | 1987-12-09 | — | — | EP | disclosed |