Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817395 | 0.87 | HIF1A (0.42) | HIF1AMEN1HPGDALOX15KMT2A | |
| SCHEMBL9817271 | 0.81 | CYP4F2 (0.39) | MEN1KMT2AMAPTHSPA5IDO1 | |
| SCHEMBL3136286 | 0.75 | MEN1 (0.50) | HIF1AMEN1HPGDALOX15KMT2A | |
| SCHEMBL9817338 | 0.73 | HPGD (0.41) | HIF1AMEN1HPGDALOX15KMT2A | |
| SCHEMBL9817288 | 0.72 | AKR1B1 (0.47) | HIF1AHSPA5IDO1AKR1B1CA2 | |
| SCHEMBL1418003 | 0.72 | HIF1A (0.59) | HIF1AMEN1HPGDALOX15KMT2A | |
| SCHEMBL7519491 | 0.72 | ALOX15 (0.59) | HIF1AMEN1HPGDALOX15KMT2A | |
| SCHEMBL9817270 | 0.71 | HDAC6 (0.41) | IDO1CA1CA12CA9 | |
| SCHEMBL9621020 | 0.70 | CYP2D6 (0.31) | MAPTLMNA | |
| SCHEMBL5724266 | 0.70 | ALOX15 (0.55) | HIF1AMEN1HPGDALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248213-B1 | HYDROXYPHENYL- AND HYDROXYPHENOXYALKANOIC ACID IODOPROPARGYL ESTERS | THE DOW CHEMICAL COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-4731466-A | FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0248213-A2 | Hydroxyphenyl- and hydroxyphenoxyalkanoic acid iodopropargyl esters | THE DOW CHEMICAL COMPANY (US) | 1987-12-09 | — | — | EP | disclosed |