Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8232660 | 0.81 | PTPRC (0.77) | PTPRCESR1ESR2MAOAUGT1A1 | |
| SCHEMBL6237857 | 0.77 | PTPRC (1.00) | PTPRCESR1ESR2MAOAUGT1A1 | |
| SCHEMBL8947876 | 0.76 | MEN1 (0.55) | PTPRCCDK5CDK5R1MAOAMAOB | |
| SCHEMBL10976626 | 0.76 | MEN1 (0.55) | PTPRCCDK5CDK5R1MAOAMAOB | |
| SCHEMBL8947834 | 0.70 | CA9 (0.41) | PTPRCMAOAMAOBCA2CA1 | |
| Methoxymethane SCHEMBL7913630 | 0.70 | MEN1 (0.48) | PTPRCMAOAMAOBKDM4EMEN1 | |
| SCHEMBL30598693 | 0.69 | PTPRC (0.59) | PTPRCESR1ESR2MAOAUGT1A1 | |
| SCHEMBL8221556 | 0.69 | PTPRC (0.59) | PTPRCESR1ESR2MAOAUGT1A1 | |
| SCHEMBL7511155 | 0.68 | ESR1 (0.58) | PTPRCESR1ESR2MAOAUGT1A1 | |
| SCHEMBL8995419 | 0.67 | POLB (0.41) | PTPRCCA2CA1CA7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077395-A | Nitrosation, sulfonation, reduction, oxidation, diazotization, alkylation or acylation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | disclosed |