SCHEMBL8995419

SCHEMBL8995419

O=C1C=Cc2cc(S(=O)(=O)O)ccc2/C1=N/O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.41
PKM P14618 2/20 0.41
ALDH1A1 P00352 9/20 0.38
KDM4E B2RXH2 7/20 0.38
HSD17B10 Q99714 5/20 0.38
MAPT P10636 3/20 0.38
HTT P42858 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
NPSR1 Q6W5P4 3/20 0.38
HPGD P15428 3/20 0.38
TSHR P16473 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
LMNA P02545 2/20 0.38
TP53 P04637 1/20 0.38
PAX8 Q06710 1/20 0.38
MAPK1 P28482 1/20 0.36
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21436584 0.97 POLB (0.40) POLBPKMALDH1A1KDM4EHSD17B10
SCHEMBL15195813 0.82 PTPRC (0.34) ALDH1A1HSD17B10TDP1PTPRCMEN1
SCHEMBL11027837 0.82 PTPRC (0.49) POLBPKMALDH1A1KDM4EHSD17B10
SCHEMBL5344213 0.80 MEN1 (0.37) ALDH1A1MAPTHTTTSHRTDP1
SCHEMBL5344218 0.80 MEN1 (0.37) ALDH1A1MAPTHTTTSHRTDP1
SCHEMBL8947834 0.76 CA9 (0.41) PKMALDH1A1KDM4EMAPTHTT
SCHEMBL21784230 0.75 GAA (0.45) POLBALDH1A1KDM4EMAPTSMN1; SMN2
SCHEMBL8373651 0.74 ALDH1A1 (0.33) ALDH1A1KDM4EHSD17B10HPGDTSHR
SCHEMBL2530021 0.72 ALDH1A1 (0.42) POLBPKMALDH1A1KDM4EHSD17B10
SCHEMBL11028594 0.71 PTPRC (0.59) POLBPKMALDH1A1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11046104-B2 Security printing INOVINK LIMITED (GB) 2021-06-29 US disclosed
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 US disclosed
US-8932370-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2015-01-13 US disclosed
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-11-06 US disclosed
US-8758451-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2014-06-24 US disclosed
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-01-16 US disclosed
US-20120272990-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2012-11-01 US disclosed
US-8187340-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2012-05-29 US disclosed
WO-2011084803-A2 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-07-14 WO disclosed
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-06-30 US disclosed
US-20090212554-A1 PRINTING INOVINK LIMITED (GB) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120272990-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 POLB 683/4885PKM 3044/4885ALDH1A1 192/4885
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 POLB 683/4885PKM 3044/4885ALDH1A1 192/4885
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 POLB 683/4885PKM 3044/4885ALDH1A1 192/4885
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 POLB 683/4885PKM 3044/4885ALDH1A1 192/4885
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 POLB 683/4885PKM 3044/4885ALDH1A1 192/4885
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 POLB 683/4885PKM 3044/4885ALDH1A1 192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.