SCHEMBL8947834

SCHEMBL8947834

Cc1ccc2c(c1)C=CC(=O)/C2=N\O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA7 P43166 1/20 0.41
PTPRC P08575 3/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
ELANE P08246 1/20 0.35
METAP1 P53582 1/20 0.34
MAPT P10636 3/20 0.33
KDM4E B2RXH2 2/20 0.33
S100A4 P26447 1/20 0.33
CDC25A P30304 1/20 0.33
CDC25C P30307 1/20 0.33
APAF1 O14727 1/20 0.33
PKM P14618 1/20 0.33
IDO1 P14902 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11858854 0.79 S100A4 (0.50) CA9CA1CA2CA4CA7
SCHEMBL16900338 0.76 PTPRC (0.53) CA9CA1CA2CA4CA7
SCHEMBL8995419 0.76 POLB (0.41) CA1CA2CA7PTPRCMAPT
SCHEMBL10976626 0.74 MEN1 (0.55) CA9CA1CA2CA7PTPRC
SCHEMBL8947876 0.74 MEN1 (0.55) CA9CA1CA2CA7PTPRC
SCHEMBL21436584 0.73 POLB (0.40) PTPRCMAPTKDM4EPKMMAPK1
Methoxymethane SCHEMBL7913630 0.72 MEN1 (0.48) PTPRCMAOAMAOBMAPTKDM4E
SCHEMBL13742982 0.71 PTPRC (0.31) PTPRC
SCHEMBL9817317 0.70 PTPRC (0.62) CA9CA1CA2CA7PTPRC
SCHEMBL30098824 0.69 CA1 (0.37) CA9CA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 US disclosed
US-9358578-B2 Printing INOVINK LIMITED (GB) 2016-06-07 US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 US disclosed
US-8932370-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2015-01-13 US disclosed
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-11-06 US disclosed
US-8758451-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2014-06-24 US disclosed
US-20140147576-A1 PRINTING INOVINK LIMITED (GB) 2014-05-29 US disclosed
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-01-16 US disclosed
US-8444715-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2013-05-21 US disclosed
US-20120272990-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2012-11-01 US disclosed
US-8187340-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2012-05-29 US disclosed
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120272990-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 CA9 63/4885CA1 606/4885CA2 820/4885
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 CA9 63/4885CA1 606/4885CA2 820/4885
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 CA9 63/4885CA1 606/4885CA2 820/4885
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 CA9 63/4885CA1 606/4885CA2 820/4885
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 CA9 63/4885CA1 606/4885CA2 820/4885
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 CA9 63/4885CA1 606/4885CA2 820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.