Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.59 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119824 | 0.86 | PTGS1 (0.68) | PTGS1SLC6A2ADRB2ADRB1CYP2D6 | |
| SCHEMBL11121118 | 0.83 | PTGS1 (0.63) | PTGS1SLC6A2ADRB2ADRB1CYP2D6 | |
| SCHEMBL21792781 | 0.81 | ADRB2 (0.69) | PTGS1SLC6A2ADRB2ADRB1CYP2D6 | |
| SCHEMBL9629567 | 0.79 | ADRB2 (0.71) | PTGS1SLC6A2ADRB2ADRB1CYP2D6 | |
| SCHEMBL9629561 | 0.79 | ADRB2 (0.71) | PTGS1SLC6A2ADRB2ADRB1CYP2D6 | |
| SCHEMBL11108671 | 0.79 | ABCB1 (0.43) | TSHRTDP1PMP22NPY1RNPY2R | |
| Hydrochloric Acid SCHEMBL28473884 | 0.78 | MAPT (0.63) | PTGS1SLC6A2ADRB2ADRB1CYP2D6 | |
| SCHEMBL11039844 | 0.77 | TDP1 (0.59) | PTGS1SLC6A2ADRB2ADRB1CYP2D6 | |
| SCHEMBL6672267 | 0.77 | ADRB2 (0.67) | PTGS1SLC6A2ADRB2ADRB1CYP2D6 | |
| SCHEMBL30001611 | 0.76 | ADRB2 (0.68) | PTGS1SLC6A2ADRB2ADRB1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041760-B1 | PROCESS FOR THE PREPARATION OF 1-ISOPROPYLAMINO-3-(4-(2-METHOXY-ETHYL)-PHENOXY)-2-PROPANOL | Aktiebolaget Hässle (SE) | 1984-03-07 | — | — | EP | claimed |
| EP-0041760-A1 | Process for the preparation of 1-isopropylamino-3-(4-(2-methoxy-ethyl)-phenoxy)-2-propanol | Aktiebolaget Hässle (SE) | 1981-12-16 | — | — | EP | claimed |
| JP-3014547-A | — | — | None | — | — | JP | disclosed |
| JP-3014547-A | — | — | None | — | — | JP | disclosed |
| JP-H0314547-A | 1-ISOPROPYLAMINO-3-(4-(1-ACETOXY-2-METHOXYETHYL)-PHENOXY)-2-PROPANOL AND ITS PREPARATION | HAESSLE:AB | 1991-01-23 | — | — | JP | disclosed |
| JP-H0314547-A | 1-ISOPROPYLAMINO-3-(4-(1-ACETOXY-2-METHOXYETHYL)-PHENOXY)-2-PROPANOL AND ITS PREPARATION | HAESSLE:AB | 1991-01-23 | — | — | JP | disclosed |
| EP-0041760-B1 | PROCESS FOR THE PREPARATION OF 1-ISOPROPYLAMINO-3-(4-(2-METHOXY-ETHYL)-PHENOXY)-2-PROPANOL | Aktiebolaget Hässle (SE) | 1984-03-07 | — | — | EP | disclosed |
| EP-0041760-A1 | Process for the preparation of 1-isopropylamino-3-(4-(2-methoxy-ethyl)-phenoxy)-2-propanol | Aktiebolaget Hässle (SE) | 1981-12-16 | — | — | EP | disclosed |
| EP-0041760-A1 | Process for the preparation of 1-isopropylamino-3-(4-(2-methoxy-ethyl)-phenoxy)-2-propanol | Aktiebolaget Hässle (SE) | 1981-12-16 | — | — | EP | disclosed |