Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.63 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metacresol SCHEMBL8917444 | 0.84 | ACHE (0.71) | ACHEIDO1ALDH1A1MAPK1CYP3A4 | |
| Ether SCHEMBL5474605 | 0.83 | ALDH1A1 (0.42) | ACHEALDH1A1MAPK1CYP3A4HTT | |
| M-Xylene SCHEMBL28720164 | 0.83 | ACHE (0.80) | ACHEIDO1ALDH1A1MAPK1CYP3A4 | |
| Toluene SCHEMBL6666240 | 0.81 | TSHR (0.61) | ACHEALDH1A1CYP2C19HTTTP53 | |
| Toluene SCHEMBL4611849 | 0.81 | TSHR (0.61) | ACHEALDH1A1CYP2C19HTTTP53 | |
| Toluene SCHEMBL8107016 | 0.81 | TSHR (0.61) | ACHEALDH1A1CYP2C19HTTTP53 | |
| Toluene SCHEMBL10589554 | 0.81 | TSHR (0.61) | ACHEALDH1A1CYP2C19HTTTP53 | |
| Toluene SCHEMBL11442347 | 0.81 | TSHR (0.61) | ACHEALDH1A1CYP2C19HTTTP53 | |
| Toluene SCHEMBL98542 | 0.81 | TSHR (0.61) | ACHEALDH1A1CYP2C19HTTTP53 | |
| Toluene SCHEMBL8432145 | 0.81 | TSHR (0.61) | ACHEALDH1A1CYP2C19HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116172869-A | Pharmaceutical compositions comprising inhibitors of Akt protein kinase | 豪夫迈·罗氏有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-109354684-B | Process for synthesizing poly (p-phenylene benzobisoxazole) | 长江师范学院 | 2021-01-05 | — | — | CN | disclosed |
| EP-3496722-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING AKT PROTEIN KINASE INHIBITORS | H. Hoffnabb-La Roche Ag (CH) | 2019-06-19 | — | — | EP | disclosed |
| WO-2018029226-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING AKT PROTEIN KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-02-15 | — | — | WO | disclosed |
| EP-0158517-B1 | PROCESS FOR THE PRODUCTION OF ETHYLENE GLYCOL | Montvale Process Company Incorporated (US) | 1991-12-11 | — | — | EP | disclosed |
| US-4608444-A | Process and accompanying catalysts for the hydroformylation of formaldehyde to glycol-aldehyde | THE HALCON SD GROUP, INC. (US) | 1986-08-26 | — | — | US | disclosed |
| US-4560806-A | Process and catalyst useful in the production of glycol aldehyde | THE HALCON SD GROUP, INC. (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0158517-A2 | Process for the production of ethylene glycol | Montvale Process Company Incorporated (US) | 1985-10-16 | — | — | EP | disclosed |
| EP-0158518-A2 | Process and accompanying catalysts for the hydroformylation of formaldehyde to glycol aldehyde | Montvale Process Company Incorporated (US) | 1985-10-16 | — | — | EP | disclosed |
| US-4496781-A | USING RHODIUM PHOSPHINE AMIDE CATALYST | THE HALCON SD GROUP, INC. (US) | 1985-01-29 | — | — | US | disclosed |