Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818198 | 0.94 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL79031 | 0.94 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL9818150 | 0.91 | KDM4E (0.57) | SMN1; SMN2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL26736145 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL5707301 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL15890450 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP3A4KDM4EMEN1KMT2A | |
| 1,3-Propanediol SCHEMBL17704098 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP3A4KDM4EMEN1KMT2A | |
| Di(Hydroxyethyl)Ether SCHEMBL9469009 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL15127221 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL16711544 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP3A4KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271649-B1 | ESTERS OF 3-TERT.-BUTYL- OR 3-TERT.-BUTYL-5-ALKYL-4-HYDROXYPHENYL(ALKAN)OIC ACIDS WITH ETHOXYLATES OF BIS-(4- OR 2-HYDROXYPHENYL) ALKANES, OXIDES, SULFIDES AND SULFONES OF TRIS-(4-HYDROXYPHENYL) ALKANES AND OF 1,3,5-BIS-(4-HYDROXYPHENYL-ISOPROPYLIDENE) ARYLENE, THEIR PREPARATION AND USE AS STABILIZERS | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-10-16 | — | — | EP | disclosed |
| US-4912249-A | Esters of 3-tert-butyl or 3-tert-butyl-5-alkyl-4-hydroxylphenyl(alkane) carboxylic acids | HUELS AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | disclosed |
| EP-0271649-A2 | Esters of 3-tert.-butyl- or 3-tert.-butyl-5-alkyl-4-hydroxyphenyl(alkan)oic acids with ethoxylates of bis-(4- or 2-hydroxyphenyl) alkanes, oxides, sulfides and sulfones of tris-(4-hydroxyphenyl) alkanes and of 1,3,5-bis-(4-hydroxyphenyl-isopropylidene) arylene, their preparation and use as stabilizers | HÜLS AKTIENGESELLSCHAFT (DE) | 1988-06-22 | — | — | EP | disclosed |