Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.50 |
| ▸ | CES2 | O00748 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8158420 | 1.00 | CES1 (0.50) | CES1CES2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL12242104 | 0.81 | TSHR (0.47) | CES1CES2MAPTSMN1; SMN2HPGD | |
| SCHEMBL15313234 | 0.81 | CES1 (0.44) | CES1CES2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL27908851 | 0.81 | CES1 (0.52) | CES1CES2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL5698372 | 0.81 | CES1 (0.52) | CES1CES2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9818176 | 0.81 | CES1 (0.52) | CES1CES2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL27713863 | 0.80 | CES1 (0.47) | CES1CES2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10768795 | 0.80 | CES1 (0.48) | CES1CES2MAPTL3MBTL1MEN1 | |
| SCHEMBL28176751 | 0.80 | CES1 (0.42) | CES1CES2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL11483327 | 0.80 | CES2 (0.57) | CES1CES2MAPTL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762948-A | USING METALLOCENYL PHOSPHINE REDUCING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-09 | — | — | US | claimed |
| US-20190031591-A1 | METHOD FOR PREPARING MULTI-SUBSTITUTED ACRYLIC ACID COMPOUND | CHANG CHUN PLASTICS CO., LTD. (TW) | 2019-01-31 | — | — | US | disclosed |
| EP-0275354-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE ARYLACETIC ACID DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-10-16 | — | — | EP | disclosed |
| US-4762948-A | USING METALLOCENYL PHOSPHINE REDUCING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-09 | — | — | US | disclosed |
| EP-0275354-A1 | Process for preparing optically active arylacetic acid derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031591-A1 | METHOD FOR PREPARING MULTI-SUBSTITUTED ACRYLIC ACID COMPOUND | GRIA4, ASNS, GRIA1 | CES1 3876/4885CES2 2964/4885MAPT 4448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.