Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD1 | P21728 | 3/20 | 0.41 |
| ▸ | DRD5 | P21918 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19453895 | 0.88 | KDM1A (0.42) | KDM1ADRD2DRD1DRD5DRD3 | |
| SCHEMBL19439341 | 0.86 | KDM1A (0.41) | KDM1ADRD2DRD1DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL9374439 | 0.82 | ATM (0.44) | — | |
| SCHEMBL22145508 | 0.79 | KDM1A (0.46) | KDM1ADRD2DRD1DRD5DRD3 | |
| SCHEMBL9374419 | 0.79 | CYP3A4 (0.42) | KDM1AHTR2A | |
| Hydrochloric Acid SCHEMBL6021932 | 0.77 | CYP3A4 (0.41) | KDM1AHTR2A | |
| SCHEMBL25438091 | 0.77 | KDM1A (0.43) | KDM1ADRD2DRD1DRD5DRD3 | |
| SCHEMBL20232227 | 0.75 | KDM1A (0.44) | KDM1ADRD2DRD1DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL9376053 | 0.72 | OPRM1 (0.37) | — | |
| SCHEMBL5305884 | 0.72 | ADRA2A (0.48) | DRD2DRD1DRD5DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3141259-A | — | — | None | — | — | JP | disclosed |
| JP-H03141259-A | BICYCLIC AMINE COMPOUND AND PRODUCTION THEREOF | FUJISAWA PHARMACEUT CO LTD | 1991-06-17 | — | — | JP | disclosed |