Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | PRNP | P04156 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456253 | 0.80 | CYSLTR1 (0.49) | CYSLTR2CYSLTR1RXFP1PRNPKDM4E | |
| SCHEMBL7455761 | 0.80 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1RXFP1PRNPKDM4E | |
| SCHEMBL7714637 | 0.79 | CYSLTR1 (0.43) | CYSLTR2CYSLTR1RXFP1PRNPKDM4E | |
| SCHEMBL7460680 | 0.79 | CYP1A2 (0.43) | CYSLTR2CYSLTR1RXFP1PRNPKDM4E | |
| Hydrogen Sulfide SCHEMBL9818421 | 0.79 | CYSLTR1 (0.48) | CYSLTR2CYSLTR1RXFP1PRNPKDM4E | |
| SCHEMBL10546745 | 0.76 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1RXFP1PRNPKDM4E | |
| SCHEMBL5373500 | 0.74 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1KDM4ECYP1A2CYP2E1 | |
| SCHEMBL9818433 | 0.73 | PDE10A (0.63) | CYSLTR2CYSLTR1PDE10AGPBAR1 | |
| SCHEMBL6641172 | 0.70 | RAB9A (0.47) | RXFP1PRNPKDM4ECYP1A2CYP2E1 | |
| SCHEMBL13058918 | 0.70 | SMN1; SMN2 (0.45) | RXFP1PRNPKDM4ECYP1A2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059610-A | QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-10-22 | — | — | US | disclosed |