Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.57 |
| ▸ | CA2 | P00918 | 6/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818471 | 0.85 | CA1 (0.57) | CA1CA2FFAR4CA12CA9 | |
| SCHEMBL5261746 | 0.81 | MEN1 (0.57) | CA1CA2PRMT1CA12CA9 | |
| SCHEMBL9818411 | 0.75 | APP (0.57) | FFAR4MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL1645913 | 0.75 | CA1 (1.00) | CA1CA2PRMT1CA12CA9 | |
| SCHEMBL8521142 | 0.73 | CA12 (0.52) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL9722737 | 0.73 | MEN1 (0.47) | CA2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL3278551 | 0.72 | POLB (0.51) | MEN1KMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL9818418 | 0.72 | ALDH1A1 (0.51) | CA2PRMT1MEN1KMT2APOLB | |
| SCHEMBL9818442 | 0.71 | ALDH1A1 (0.46) | CA1CA2FFAR4MEN1KMT2A | |
| SCHEMBL9818477 | 0.71 | HPGD (0.59) | FFAR4MEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997921-A | Substituted phenylazosulfoindole dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4954563-A | Polyamide dye | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |