Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278551 | 0.90 | POLB (0.51) | APPMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL9818407 | 0.90 | GAA (0.56) | APPMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL8143772 | 0.86 | HTR6 (0.52) | APPMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL5261746 | 0.86 | MEN1 (0.57) | MEN1KMT2AALDH1A1MAPK1CYP3A4 | |
| SCHEMBL9818432 | 0.83 | HTR6 (0.61) | ALDH1A1POLBGAAKDM4EHPGD | |
| SCHEMBL9722737 | 0.81 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPK1CYP3A4 | |
| SCHEMBL13241502 | 0.79 | KMT2A (0.53) | APPMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL9722812 | 0.78 | CA2 (0.57) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL9299326 | 0.77 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1CYP3A4POLB | |
| SCHEMBL9818418 | 0.76 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997921-A | Substituted phenylazosulfoindole dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4954563-A | Polyamide dye | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |