Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389367 | 0.76 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1LMNAMAPTHTT | |
| SCHEMBL17035134 | 0.72 | SCN9A (0.46) | LMNAMAPTHTTSCN9ACYP2A6 | |
| SCHEMBL10390196 | 0.72 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1HTR6GAA | |
| SCHEMBL10661698 | 0.71 | CYP3A4 (0.52) | MAPTGAAS100A4CA1CA2 | |
| SCHEMBL19152440 | 0.70 | S100A4 (0.53) | HSP90AA1HSP90AB1DNMT1LMNAMAPT | |
| SCHEMBL31195807 | 0.70 | DNMT1 (0.54) | HSP90AA1HSP90AB1DNMT1MAPTCYP2A6 | |
| SCHEMBL14670621 | 0.70 | DNMT1 (0.64) | HSP90AA1HSP90AB1DNMT1LMNAMAPT | |
| SCHEMBL31106330 | 0.70 | S100A4 (0.53) | HSP90AA1HSP90AB1DNMT1LMNAMAPT | |
| SCHEMBL22289446 | 0.70 | DNMT1 (0.54) | HSP90AA1HSP90AB1DNMT1MAPTCYP2A6 | |
| SCHEMBL10388961 | 0.70 | HTR6 (0.53) | DNMT1MAPTHTR6GAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997921-A | Substituted phenylazosulfoindole dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4954563-A | Polyamide dye | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |