Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22667997 | 0.83 | POLB (0.44) | POLBNPC1MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL27894718 | 0.79 | NPC1 (0.50) | POLBNPC1MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL859246 | 0.79 | NPC1 (0.50) | POLBNPC1MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL27916120 | 0.79 | NPC1 (0.50) | POLBNPC1MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL860756 | 0.79 | NPC1 (0.50) | POLBNPC1MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL15209780 | 0.78 | SLC9A1 (0.46) | POLBKDM4EMEN1MAPTKMT2A | |
| SCHEMBL10992734 | 0.74 | POLB (0.55) | POLBALDH1A1KDM4ETP53TSHR | |
| SCHEMBL1816971 | 0.74 | POLB (0.55) | POLBALDH1A1HPGDMEN1MAPT | |
| SCHEMBL15428731 | 0.74 | POLB (0.55) | POLBALDH1A1KDM4E | |
| SCHEMBL544410 | 0.74 | POLB (0.55) | POLBHPGDMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001227-A | Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand | CIBA-GEIGY CORPORATION (US) | 1991-03-19 | — | — | US | claimed |
| US-5001227-A | Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand | CIBA-GEIGY CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| US-4185013-A | Anionic azo dyes having a 3-dibenzofuranyl diazo component radical optionally having a 2- or 8-sulfo group | SANDOZ LTD. (CH) | 1980-01-22 | — | — | US | disclosed |
| US-4081438-A | Anionic azo dyes having a 3-dibenzofuranyl diazo component radical optionally having A2-or 8-sulfo group | SANDOZ LTD. (CH) | 1978-03-28 | — | — | US | disclosed |