Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10555025 | 0.89 | REN (0.56) | REN | |
| SCHEMBL9417321 | 0.89 | REN (0.56) | REN | |
| SCHEMBL10794397 | 0.89 | REN (0.67) | REN | |
| SCHEMBL9417437 | 0.77 | REN (0.66) | REN | |
| SCHEMBL9057406 | 0.75 | PSEN1 (0.48) | REN | |
| SCHEMBL10337125 | 0.75 | PSEN1 (0.48) | REN | |
| SCHEMBL7404966 | 0.75 | PSEN1 (0.48) | REN | |
| SCHEMBL7337682 | 0.75 | REN (0.61) | REN | |
| SCHEMBL7337568 | 0.75 | REN (0.61) | REN | |
| SCHEMBL9417330 | 0.75 | PSEN1 (0.47) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032577-A | Hypotensive | ABBOTT LABORATORIES (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0295294-A4 | PEPTIDYLAMINODIOLS. | ABBOTT LAB (US) | 1990-04-10 | — | — | EP | disclosed |
| EP-0295294-A1 | PEPTIDYLAMINODIOLS | ABBOTT LABORATORIES (US) | 1988-12-21 | — | — | EP | disclosed |
| WO-1988005050-A1 | PEPTIDYLAMINODIOLS | ABBOTT LABORATORIES (US) | 1988-07-14 | — | — | WO | disclosed |
| EP-0229667-A2 | Peptidylaminodiols | ABBOTT LABORATORIES (US) | 1987-07-22 | — | — | EP | disclosed |