Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | MAX | P61244 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | GLB1 | P16278 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367595 | 0.82 | TYR (0.58) | SIRT2SIRT1SIRT5TYRPIM1 | |
| Methane SCHEMBL11025053 | 0.80 | TYR (0.56) | SIRT2SIRT1SIRT5TYRPIM1 | |
| SCHEMBL9818675 | 0.79 | ALDH1A1 (0.44) | PIM1POLBKDM4EALDH1A1GSK3A | |
| SCHEMBL10489047 | 0.75 | IGF1R (0.46) | PIM1MYCMAXIGF1RKDM4E | |
| Styrene SCHEMBL286196 | 0.75 | ALDH1A1 (0.61) | SIRT2SIRT1SIRT5PIM1POLB | |
| Styrene SCHEMBL5583611 | 0.75 | ALDH1A1 (0.61) | SIRT2SIRT1SIRT5PIM1POLB | |
| Styrene SCHEMBL9418540 | 0.75 | ALDH1A1 (0.61) | SIRT2SIRT1SIRT5PIM1POLB | |
| SCHEMBL30560616 | 0.72 | TYR (0.47) | SIRT2SIRT1SIRT5TYRPOLB | |
| SCHEMBL27747255 | 0.72 | GSK3B (0.44) | KDM4EMAPK1ALDH1A1GSK3AGSK3B | |
| SCHEMBL6281528 | 0.69 | ALDH1A1 (0.58) | SIRT2SIRT1SIRT5TYRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0140273-B1 | POSITIVE PHOTORESIST COMPOSITIONS HAVING DEEP UV RESPONSE, PHOTOSENSITIVE ELEMENTS AND THERMALLY STABLE PHOTOCHEMICALLY IMAGED SYSTEMS CONTAINING SAME | HOECHST CELANESE CORPORATION (US) | 1991-09-11 | — | — | EP | disclosed |