Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26315 | 0.87 | TSHR (0.40) | TDP1KCNH2TSHR | |
| Ammonia Solution, Strong SCHEMBL7710344 | 0.85 | TSHR (0.39) | TDP1KCNH2TSHR | |
| SCHEMBL137792 | 0.79 | TSHR (0.39) | TSHR | |
| SCHEMBL21722328 | 0.79 | TSHR (0.33) | TDP1TSHR | |
| Hydrochloric Acid SCHEMBL1302903 | 0.78 | TSHR (0.38) | TSHR | |
| Fluoride SCHEMBL1301660 | 0.78 | TSHR (0.38) | TSHR | |
| Iodide SCHEMBL1302850 | 0.78 | TSHR (0.38) | TSHR | |
| Bromide SCHEMBL1303250 | 0.78 | TSHR (0.38) | TSHR | |
| Acrylamide SCHEMBL8960992 | 0.77 | TSHR (0.34) | TSHR | |
| SCHEMBL20001689 | 0.77 | CHRNB2 (0.39) | TDP1TSHRCHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213317-B1 | BASE-CATALYZED, LOW TEMPERATURE SELF-CROSSLINKING POLYMERS | National Starch and Chemical Investment Holding Corporation (US) | 1991-12-04 | — | — | EP | claimed |
| US-4788267-A | CONTAINING HALOHYDRIN MONOMER AND AMINE SALT MONOMER | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1988-11-29 | — | — | US | claimed |
| EP-0213317-A2 | Base-catalyzed, low temperature self-crosslinking polymers | National Starch and Chemical Investment Holding Corporation (US) | 1987-03-11 | — | — | EP | claimed |