Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26315 | 0.98 | TSHR (0.40) | TSHRKCNH2CHRM2CHRM4CHRM1 | |
| SCHEMBL9818650 | 0.85 | TDP1 (0.43) | TSHRKCNH2TDP1 | |
| SCHEMBL6517414 | 0.80 | TSHR (0.37) | TSHRKCNH2CHRM2CHRM4CHRM1 | |
| SCHEMBL25362541 | 0.79 | KCNH2 (0.31) | TSHRKCNH2 | |
| SCHEMBL611932 | 0.77 | TSHR (0.39) | TSHRKCNH2CHRM2CHRM4CHRM1 | |
| SCHEMBL20001689 | 0.77 | CHRNB2 (0.39) | TSHRCHRM2CHRM4CHRM1LMNA | |
| SCHEMBL11549731 | 0.77 | CHRNB2 (0.39) | CHRM2CHRM4CHRM1 | |
| SCHEMBL7718350 | 0.77 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL137792 | 0.77 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL28669002 | 0.77 | ALDH1A1 (0.39) | TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6361940-B1 | IMMOBILIZATION; GENETIC ENGINEERING | QIAGEN GENOMICS, INC. | 2002-03-26 | — | — | US | disclosed |