Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMOX | Q9NWM0 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16253865 | 0.78 | GAA (0.42) | GAAGFERMAOAMEN1KMT2A | |
| SCHEMBL10765717 | 0.74 | MAOA (0.41) | GAAGFERMAOAMEN1KMT2A | |
| SCHEMBL16253864 | 0.74 | MAPT (0.46) | GAAGFERMAOAMEN1KMT2A | |
| SCHEMBL10765724 | 0.74 | KCNH3 (0.41) | GAAGFERMAOAMEN1KMT2A | |
| SCHEMBL10769032 | 0.74 | — | — | |
| SCHEMBL11356692 | 0.68 | HRH2 (0.59) | — | |
| SCHEMBL17742100 | 0.68 | GAA (0.61) | GAAGFERMAOASMOXKDM1A | |
| SCHEMBL17742105 | 0.66 | MAOA (0.60) | GAAGFERMAOASMOXKDM1A | |
| SCHEMBL17741774 | 0.66 | MAOA (0.50) | GAAGFERMAOAMEN1KMT2A | |
| SCHEMBL17742109 | 0.66 | MAOA (0.48) | GAAGFERMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028716-A | Lipid Peroxidation Inhibitors | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0381439-A1 | Triazole derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-08-08 | — | — | EP | disclosed |