Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818716 | 0.91 | NPC1 (0.59) | LMNAMAPTRAB9ACNR1MEN1 | |
| SCHEMBL9818694 | 0.86 | CNR1 (0.62) | ALDH1A1MAPTRAB9ACNR1MEN1 | |
| SCHEMBL9818724 | 0.85 | CNR1 (0.63) | ALDH1A1LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9818668 | 0.83 | CNR1 (0.70) | ALDH1A1LMNACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL9818721 | 0.82 | CNR1 (0.63) | ALDH1A1LMNACYP3A4MAPTCYP2C19 | |
| SCHEMBL9818621 | 0.82 | CNR1 (0.66) | ALDH1A1LMNAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL300331 | 0.82 | CNR1 (0.72) | ALDH1A1LMNACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL9818592 | 0.80 | CNR1 (0.63) | ALDH1A1LMNAMAPTCYP2C9CYP2C19 | |
| SCHEMBL9818669 | 0.80 | CNR1 (0.87) | ALDH1A1LMNACYP2D6MAPTRAB9A | |
| SCHEMBL9818576 | 0.80 | LMNA (0.68) | ALDH1A1LMNACYP3A4CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015644-A | Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds | WARNER-LAMBERT COMPANY (US) | 1991-05-14 | — | — | US | disclosed |