SCHEMBL98189

SCHEMBL98189

CCC[C]c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.41
TSHR P16473 1/20 0.38
TP53 P04637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
THPO P40225 1/20 0.36
LTA4H P09960 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
HTR2A P28223 1/20 0.34
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95799 0.85 LTA4H (0.42) APPTP53CYP3A4LTA4HHTT
SCHEMBL95929 0.83 LTA4H (0.42) TSHRTP53CYP3A4LTA4HHTT
SCHEMBL7194368 0.81 DNM1 (0.44) TSHRTP53CYP3A4LTA4HHTT
SCHEMBL4732470 0.81 DNM1 (0.44) TSHRTP53CYP3A4LTA4HHTT
SCHEMBL96978 0.78
SCHEMBL9784179 0.75 CYP1A2 (0.54) APPNPSR1CYP1A2CYP3A4CYP2C9
SCHEMBL613220 0.75 CYP1A2 (0.54) APPNPSR1CYP1A2CYP3A4CYP2C9
SCHEMBL9094995 0.70 NPSR1 (0.44) APPNPSR1CYP1A2CYP3A4CYP2C9
SCHEMBL5608616 0.69 MAPT (0.38) APPTSHRCYP1A2CYP3A4CYP2C9
SCHEMBL17185720 0.69 AOC3 (0.36) APPTSHRTP53NPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111806132-A Decorative panel, panel covering and method for producing such a decorative panel 诺森建筑产业有限公司 2020-10-23 CN claimed
CN-105324424-B The composition being made of the Synergistic mixtures of thermoplastic polymer and specific amino ether and particulate phosphinates 克拉里安特国际有限公司 2019-04-12 CN claimed
CN-109195975-A Diazaspiro [5.5] undecane derivative and application thereof 四川海思科制药有限公司 2019-01-11 CN claimed
CN-105324424-A Composition comprising a thermoplastic polymer and a synergistic mixture of determined amino ethers and finely-particled phosphinates CLARIANT INT LTD 2016-02-10 CN claimed
WO-2008059014-A2 ANTITUBERCULOSIS AGENTS WITH ALKYLIDENE OR ALKYL SIDE CHAIN UNIVERSIDAD DE SALAMANCA (ES) 2008-05-22 WO claimed
CN-111806132-A Decorative panel, panel covering and method for producing such a decorative panel 诺森建筑产业有限公司 2020-10-23 CN disclosed
CN-105324424-B The composition being made of the Synergistic mixtures of thermoplastic polymer and specific amino ether and particulate phosphinates 克拉里安特国际有限公司 2019-04-12 CN disclosed
CN-109195975-A Diazaspiro [5.5] undecane derivative and application thereof 四川海思科制药有限公司 2019-01-11 CN disclosed
EP-3131965-A1 METHODS OF PREPARING COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES AND METHODS OF USING SAME Valspar Sourcing, Inc. (US) 2017-02-22 EP disclosed
CN-105324424-A Composition comprising a thermoplastic polymer and a synergistic mixture of determined amino ethers and finely-particled phosphinates CLARIANT INT LTD 2016-02-10 CN disclosed
WO-2015160788-A1 METHODS OF PREPARING COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES AND METHODS OF USING SAME VALSPAR SOURCING, INC. (US) 2015-10-22 WO disclosed
EP-2882818-A1 STABILIZER AND COATING COMPOSITIONS THEREOF Valspar Sourcing, Inc. (US) 2015-06-17 EP disclosed
EP-0641781-A1 4-AMINO(ALKYL)CYCLOHEXANE-1-CARBOXAMIDE COMPOUND AND USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1995-03-08 EP disclosed
US-5245034-A Compound having vessel smooth muscle relaxation activity Hidaka, Kiroyoshi (JP) 1993-09-14 US disclosed
US-5216150-A Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor Hidaka, Hiroyoshi (JP) 1993-06-01 US disclosed
US-5081246-A Isoquinolino sulfonamino derivatives Hidaka, Hiroyoshi (JP) 1992-01-14 US disclosed
US-4735959-A HYPOGLYCEMIC AGENTS DR. KARL THOMAE GMBH (DE) 1988-04-05 US disclosed
US-4329350-A VASODILATORS RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1982-05-11 US disclosed
EP-0032681-A2 Hindered bis-phenol phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-07-29 EP disclosed
US-4021421-A ENZYME INDUCING ACTIVITY RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1977-05-03 US disclosed