SCHEMBL9819624

SCHEMBL9819624

O=C(CCl)NCCCNc1ccc(O)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.53
MEN1 O00255 7/20 0.52
KMT2A Q03164 7/20 0.52
BLM P54132 5/20 0.52
POLB P06746 4/20 0.52
NSD2 O96028 3/20 0.52
RXFP1 Q9HBX9 1/20 0.52
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
MTOR P42345 2/20 0.49
SIRT2 Q8IXJ6 1/20 0.49
NQO1 P15559 3/20 0.48
TOP2B Q02880 1/20 0.48
MAPT P10636 4/20 0.47
MAOA P21397 1/20 0.47
SMN1; SMN2 Q16637 5/20 0.46
HIF1A Q16665 2/20 0.46
BRCA1 P38398 1/20 0.46
LMNA P02545 4/20 0.45
MAPK1 P28482 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9819609 0.88 NSD2 (0.52) CYP19A1MEN1KMT2ABLMPOLB
SCHEMBL20334207 0.86 CYP19A1 (0.55) CYP19A1MEN1KMT2ABLMPOLB
SCHEMBL9819774 0.85 MEN1 (0.60) MEN1KMT2ABLMPOLBNSD2
SCHEMBL20334355 0.82 CYP19A1 (0.58) CYP19A1MEN1KMT2ABLMPOLB
SCHEMBL6661577 0.81 CYP19A1 (0.80) CYP19A1MEN1KMT2ABLMPOLB
SCHEMBL16318733 0.81 CYP19A1 (0.61) CYP19A1MEN1KMT2ABLMPOLB
SCHEMBL11141088 0.80 CYP19A1 (0.60) CYP19A1MEN1KMT2ABLMPOLB
SCHEMBL6666259 0.80 CYP19A1 (0.73) CYP19A1MEN1KMT2ABLMPOLB
SCHEMBL8431029 0.80 CYP19A1 (0.60) CYP19A1MEN1KMT2ABLMPOLB
SCHEMBL14496107 0.80 MEN1 (0.56) CYP19A1MEN1KMT2ABLMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 US disclosed
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 US disclosed
EP-3558235-B1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION OREAL (FR) 2021-09-08 EP disclosed
WO-2018115337-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2018-06-28 WO disclosed
US-5009880-A Mixture of an anionic and cationic polymer for shampoos, skin lotions, nail strengtheners and hair dyeing; improved fixing and anchoring; smoothness; gloss L'OREAL (FR) 1991-04-23 US disclosed
US-4719099-A ANIONIC AND CATIONIC L'OREAL (FR) 1988-01-12 US disclosed
US-4445521-A ANIONIC AND CATIONIC POLYMER COMBINATION L'OREAL (FR) 1984-05-01 US disclosed
US-4240450-A HAIR CONDITIONER OF ANIONIC POLYMERS AND CATIONIC POLYMERS L'OREAL (FR) 1980-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION KRT18, CUTA, KLK5 CYP19A1 1250/4885MEN1 2794/4885KMT2A 2181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.