SCHEMBL9819609

SCHEMBL9819609

CNc1ccc(NCCCNC(=O)CCl)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 2/20 0.52
MEN1 O00255 2/20 0.52
POLB P06746 2/20 0.52
BLM P54132 2/20 0.52
KMT2A Q03164 2/20 0.52
RXFP1 Q9HBX9 1/20 0.52
TOP2B Q02880 1/20 0.48
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
MTOR P42345 1/20 0.46
SIRT2 Q8IXJ6 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.44
MAPT P10636 3/20 0.44
MAPK1 P28482 3/20 0.44
EGFR P00533 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
PABPC1 P11940 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6939275 0.88 MEN1 (0.56) NSD2MEN1POLBBLMKMT2A
SCHEMBL9819624 0.88 CYP19A1 (0.53) NSD2MEN1POLBBLMKMT2A
SCHEMBL20333877 0.87 NSD2 (0.55) NSD2MEN1POLBBLMKMT2A
SCHEMBL9819774 0.85 MEN1 (0.60) NSD2MEN1POLBBLMKMT2A
SCHEMBL23787802 0.84 MEN1 (0.52) NSD2MEN1POLBBLMKMT2A
SCHEMBL23787768 0.83 MEN1 (0.54) NSD2MEN1POLBBLMKMT2A
SCHEMBL23787751 0.82 MEN1 (0.55) NSD2MEN1POLBBLMKMT2A
SCHEMBL20333893 0.82 MEN1 (0.49) NSD2MEN1POLBBLMKMT2A
SCHEMBL23787839 0.81 MEN1 (0.48) NSD2MEN1POLBBLMKMT2A
SCHEMBL20710632 0.81 TOP2B (0.62) NSD2MEN1POLBBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 US disclosed
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 US disclosed
EP-3558235-B1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION OREAL (FR) 2021-09-08 EP disclosed
WO-2018115337-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2018-06-28 WO disclosed
US-5009880-A Mixture of an anionic and cationic polymer for shampoos, skin lotions, nail strengtheners and hair dyeing; improved fixing and anchoring; smoothness; gloss L'OREAL (FR) 1991-04-23 US disclosed
US-4719099-A ANIONIC AND CATIONIC L'OREAL (FR) 1988-01-12 US disclosed
US-4445521-A ANIONIC AND CATIONIC POLYMER COMBINATION L'OREAL (FR) 1984-05-01 US disclosed
US-4425132-A HAIR DYES, APPLYING WITHOUT RINSING L'OREAL (FR) 1984-01-10 US disclosed
US-4240450-A HAIR CONDITIONER OF ANIONIC POLYMERS AND CATIONIC POLYMERS L'OREAL (FR) 1980-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION KRT18, CUTA, KLK5 NSD2 2000/4885MEN1 2794/4885POLB 1247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.