SCHEMBL9819625

SCHEMBL9819625

C=CC(=O)NC(CC)CCCC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.46
ZDHHC2 Q9UIJ5 1/20 0.46
TSHR P16473 3/20 0.45
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
PLA2G2C Q5R387 3/20 0.39
CA2 P00918 6/20 0.39
CA1 P00915 4/20 0.39
MAPK1 P28482 1/20 0.38
CTSK P43235 1/20 0.38
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7211081 0.95 ZDHHC20 (0.49) ZDHHC20ZDHHC2TSHRTAS1R3TAS1R1
SCHEMBL8808568 0.93 ZDHHC20 (0.51) ZDHHC20ZDHHC2TSHRPLA2G2CMAPK1
SCHEMBL6514878 0.93 ZDHHC20 (0.51) ZDHHC20ZDHHC2TSHRPLA2G2CMAPK1
SCHEMBL9314536 0.93 ZDHHC20 (0.51) ZDHHC20ZDHHC2TSHRPLA2G2CMAPK1
SCHEMBL27456857 0.92 ZDHHC20 (0.48) ZDHHC20ZDHHC2TSHRTAS1R3TAS1R1
SCHEMBL1079331 0.89 ZDHHC20 (0.50) ZDHHC20ZDHHC2TSHRTAS1R3TAS1R1
SCHEMBL10877800 0.89 TAS1R3 (0.51) ZDHHC20ZDHHC2TSHRTAS1R3TAS1R1
SCHEMBL6566575 0.89 TAS1R3 (0.50) ZDHHC20ZDHHC2TSHRTAS1R3TAS1R1
SCHEMBL9314528 0.87 ZDHHC20 (0.53) ZDHHC20ZDHHC2TSHRTAS1R3TAS1R1
SCHEMBL15846224 0.86 TSHR (0.42) ZDHHC20ZDHHC2TSHRTAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5009880-A Mixture of an anionic and cationic polymer for shampoos, skin lotions, nail strengtheners and hair dyeing; improved fixing and anchoring; smoothness; gloss L'OREAL (FR) 1991-04-23 US disclosed
US-4719099-A ANIONIC AND CATIONIC L'OREAL (FR) 1988-01-12 US disclosed
EP-0134483-A2 Skin care composition S.C. JOHNSON & SON, INC. (US) 1985-03-20 EP disclosed
US-4445521-A ANIONIC AND CATIONIC POLYMER COMBINATION L'OREAL (FR) 1984-05-01 US disclosed
US-4240450-A HAIR CONDITIONER OF ANIONIC POLYMERS AND CATIONIC POLYMERS L'OREAL (FR) 1980-12-23 US disclosed