Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883583 | 0.83 | CES2 (0.52) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL10380718 | 0.80 | FAAH (0.48) | CES2CES1MEN1FAAHKMT2A | |
| SCHEMBL115180 | 0.80 | CES2 (0.48) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL116649 | 0.80 | CES2 (0.48) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL737892 | 0.80 | CES2 (0.48) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL6016882 | 0.76 | FAAH (0.44) | CES2CES1MEN1FAAHKMT2A | |
| SCHEMBL115276 | 0.76 | FAAH (0.44) | CES2CES1MEN1FAAHKMT2A | |
| SCHEMBL11172888 | 0.76 | CES2 (0.61) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL28127109 | 0.76 | CES2 (0.61) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL28650034 | 0.76 | CES2 (0.61) | CES2CES1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5009880-A | Mixture of an anionic and cationic polymer for shampoos, skin lotions, nail strengtheners and hair dyeing; improved fixing and anchoring; smoothness; gloss | L'OREAL (FR) | 1991-04-23 | — | — | US | disclosed |
| US-4719099-A | ANIONIC AND CATIONIC | L'OREAL (FR) | 1988-01-12 | — | — | US | disclosed |
| US-4445521-A | ANIONIC AND CATIONIC POLYMER COMBINATION | L'OREAL (FR) | 1984-05-01 | — | — | US | disclosed |
| US-4240450-A | HAIR CONDITIONER OF ANIONIC POLYMERS AND CATIONIC POLYMERS | L'OREAL (FR) | 1980-12-23 | — | — | US | disclosed |