Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 3/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212818 | 1.00 | SIGMAR1 (0.52) | SIGMAR1KCNH2CETPNAAADNM1 | |
| SCHEMBL9819988 | 1.00 | SIGMAR1 (0.52) | SIGMAR1KCNH2CETPNAAADNM1 | |
| SCHEMBL9035864 | 0.94 | KCNH2 (0.49) | SIGMAR1KCNH2CETPNAAADNM1 | |
| SCHEMBL9034876 | 0.92 | KCNH2 (0.61) | SIGMAR1KCNH2NAAAMIFHTR2A | |
| SCHEMBL10444157 | 0.92 | KCNH2 (0.56) | SIGMAR1KCNH2CETPNAAAMIF | |
| SCHEMBL9819846 | 0.92 | KCNH2 (0.61) | SIGMAR1KCNH2NAAAMIFHTR2A | |
| SCHEMBL9819966 | 0.92 | KCNH2 (0.61) | SIGMAR1KCNH2NAAAMIFHTR2A | |
| SCHEMBL9213359 | 0.92 | KCNH2 (0.61) | SIGMAR1KCNH2NAAAMIFHTR2A | |
| SCHEMBL9038087 | 0.92 | KCNH2 (0.56) | SIGMAR1KCNH2CETPNAAAMIF | |
| SCHEMBL9819824 | 0.92 | KCNH2 (0.56) | SIGMAR1KCNH2CETPNAAAMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |