Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | GLS | O94925 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3911743 | 0.91 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7327104 | 0.81 | GRIN2B (0.71) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL3902195 | 0.79 | ALDH1A1 (0.84) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL3906094 | 0.79 | MAPK1 (0.62) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7322213 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL15362563 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL11228856 | 0.73 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL6963770 | 0.72 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL4399146 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL16378590 | 0.72 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |