Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393244 | 0.92 | TSHR (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL18960286 | 0.85 | TSHR (0.38) | TSHRALDH1A1THRB | |
| SCHEMBL10793406 | 0.84 | TSHR (0.35) | TSHRALDH1A1THRB | |
| SCHEMBL396535 | 0.78 | TSHR (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL9715000 | 0.77 | TSHR (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL332603 | 0.75 | TSHR (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL1046024 | 0.75 | TSHR (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL9411488 | 0.75 | TSHR (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL396761 | 0.75 | TSHR (0.48) | TSHRALDH1A1THRB | |
| SCHEMBL3622859 | 0.75 | TSHR (0.40) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215817-B1 | CONTINUOUS-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4829137-A | Continuous-wear highly oxygen permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1989-05-09 | — | — | US | disclosed |
| EP-0215817-A1 | CONTINUOUS-WEAR LENSES. | BAUSCH & LOMB (US) | 1987-04-01 | — | — | EP | disclosed |
| WO-1986004341-A1 | CONTINUOUS-WEAR LENSES | BAUSCH AND LOMB INCORPORATED (US) | 1986-07-31 | — | — | WO | disclosed |
| US-4535138-A | Silane ester contact lens composition, article and method of manufacture | PARAGON OPTICAL, INC. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4419505-A | HYDROXYSILYLALKYL (METH)ACRYLATE COPOLYMER | PARAGON OPTICAL, INC. (US) | 1983-12-06 | — | — | US | disclosed |