SCHEMBL9820032

SCHEMBL9820032

Cc1cccc2oc(-c3ccc(F)cc3)nc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UTRN P46939 1/20 0.54
CEPT1 Q9Y6K0 1/20 0.52
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
HTR3A P46098 1/20 0.44
TNKS O95271 1/20 0.43
TNKS2 Q9H2K2 1/20 0.43
PARP2 Q9UGN5 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
PSEN1 P49768 1/20 0.43
PSEN2 P49810 1/20 0.43
APH1B Q8WW43 1/20 0.43
NCSTN Q92542 1/20 0.43
APH1A Q96BI3 1/20 0.43
PSENEN Q9NZ42 1/20 0.43
F2RL3 Q96RI0 4/20 0.43
TP53 P04637 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16231622 0.92 CEPT1 (0.54) UTRNCEPT1NPC1RAB9AF2RL3
SCHEMBL13494491 0.87 SMN1; SMN2 (0.51) UTRNCEPT1GAATNKSTNKS2
SCHEMBL7298455 0.85 CEPT1 (0.52) CEPT1NPC1RAB9AF2RL3SMN1; SMN2
SCHEMBL1921033 0.84 NPC1 (0.57) CEPT1GAATNKSTNKS2NPC1
SCHEMBL4584419 0.84 CEPT1 (0.49) CEPT1MGAMGAASIMGAM2
SCHEMBL18935933 0.83 TNKS (0.47) UTRNCEPT1TNKSTNKS2PARP2
SCHEMBL5361782 0.83 CEPT1 (0.48) UTRNCEPT1NPC1RAB9AF2RL3
SCHEMBL5361789 0.83 CEPT1 (0.48) UTRNCEPT1NPC1RAB9AF2RL3
SCHEMBL9468098 0.82 UTRN (0.52) UTRNHTR3ANPC1RAB9APSEN1
SCHEMBL24871289 0.81 NPC1 (0.61) UTRNCEPT1TNKSTNKS2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0182061-B1 NEW PROCESS FOR PREPARING 2(4-FLUOROPHENYL) ALPHA METHYL-5-BENZOXAZOLE ACETIC ACID RAVIZZA S.p.A. (IT) 1991-12-27 EP claimed