Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372841 | 0.81 | POLB (0.51) | ERN1POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4272786 | 0.72 | RECQL (0.47) | ERN1POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31276737 | 0.71 | ALDH1A1 (0.42) | ERN1POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29079868 | 0.71 | ALDH1A1 (0.42) | ERN1POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL19330363 | 0.70 | ERN1 (0.43) | ERN1POLBLMNASMN1; SMN2PRKDC | |
| SCHEMBL2674287 | 0.69 | CYP1A2 (0.44) | ERN1POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL19353921 | 0.69 | ERN1 (0.56) | ERN1POLB | |
| SCHEMBL27429280 | 0.68 | ERN1 (0.34) | ERN1POLBALDH1A1KDM4EHPGD | |
| SCHEMBL18510117 | 0.68 | ERN1 (0.44) | ERN1POLBLMNASMN1; SMN2PRKDC | |
| SCHEMBL746493 | 0.68 | ERN1 (0.44) | ERN1PRKDCALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104876-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-12-27 | — | — | EP | disclosed |
| US-4631081-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1986-12-23 | — | — | US | disclosed |
| EP-0104876-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-04-04 | — | — | EP | disclosed |