Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27429276 | 0.77 | POLB (0.39) | ERN1POLBKDM4EALDH1A1HPGD | |
| SCHEMBL27424939 | 0.75 | ERN1 (0.41) | ERN1POLBKDM4EALDH1A1HPGD | |
| SCHEMBL6342488 | 0.73 | ALDH1A1 (0.38) | ERN1POLBKDM4EALDH1A1HPGD | |
| SCHEMBL9820074 | 0.68 | ERN1 (0.43) | ERN1POLBKDM4EALDH1A1HPGD | |
| SCHEMBL8897224 | 0.66 | POLB (0.49) | ERN1POLBKDM4EALDH1A1HPGD | |
| SCHEMBL27608116 | 0.65 | PPARG (0.45) | ALDH1A1 | |
| SCHEMBL6557136 | 0.64 | POLB (0.41) | ERN1POLBALDH1A1 | |
| SCHEMBL4272786 | 0.63 | RECQL (0.47) | ERN1POLBKDM4EALDH1A1HPGD | |
| SCHEMBL29079868 | 0.62 | ALDH1A1 (0.42) | ERN1POLBKDM4EALDH1A1HPGD | |
| SCHEMBL31276737 | 0.62 | ALDH1A1 (0.42) | ERN1POLBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1107158-A | Polysubstituted 2-amino-thiazole derivatives | SANOFI ELF (FR) | 1995-08-23 | — | — | CN | disclosed |