Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820088 | 0.88 | GAA (0.42) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL2710907 | 0.81 | LDHA (0.38) | LDHASRRFFAR3TSHRMGAM | |
| SCHEMBL2967817 | 0.79 | LDHA (0.36) | LDHASRRFFAR3TSHRMGAM | |
| SCHEMBL620518 | 0.77 | LDHA (0.35) | LDHASRRFFAR3TSHRMGAM | |
| SCHEMBL3929483 | 0.77 | CYP2D6 (0.35) | LDHASRRFFAR3TSHRMGAM | |
| SCHEMBL10770038 | 0.76 | LDHA (0.33) | LDHASRRFFAR3TSHRMGAM | |
| SCHEMBL10550164 | 0.76 | LDHA (0.33) | LDHASRRFFAR3TSHRMGAM | |
| SCHEMBL4938475 | 0.76 | LDHA (0.33) | LDHASRRFFAR3TSHRMGAM | |
| SCHEMBL9064548 | 0.75 | ALOX15 (0.35) | — | |
| SCHEMBL9064546 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268460-B1 | NEW PERCUTANEOUS ABSORPTION ENHANCERS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE | Macrochem Corporation (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0268460-A1 | New percutaneous absorption enhancers, compositions containing same and method of use | Macrochem Corporation (US) | 1988-05-25 | — | — | EP | disclosed |