Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771656 | 0.94 | LMNA (0.60) | LMNAMAPTALDH1A1HCAR3POLB | |
| SCHEMBL9820245 | 0.86 | LMNA (0.55) | LMNAMAPTALDH1A1HCAR3POLB | |
| SCHEMBL9771699 | 0.82 | ALDH1A1 (0.54) | LMNAMAPTALDH1A1HCAR3POLB | |
| SCHEMBL14960085 | 0.81 | LMNA (0.46) | LMNAMAPTALDH1A1HCAR3POLB | |
| Ammonia Solution, Strong SCHEMBL9820251 | 0.80 | MAPT (0.40) | LMNAMAPTALDH1A1HCAR3POLB | |
| SCHEMBL15423129 | 0.79 | MAPT (0.43) | LMNAMAPTALDH1A1HCAR3POLB | |
| SCHEMBL9771611 | 0.76 | LMNA (0.59) | LMNAMAPTALDH1A1HCAR3POLB | |
| SCHEMBL9771713 | 0.76 | MAPT (0.46) | LMNAMAPTALDH1A1POLBMEN1 | |
| SCHEMBL2549528 | 0.76 | LMNA (0.52) | LMNAMAPTALDH1A1HCAR3POLB | |
| SCHEMBL9771617 | 0.74 | MAPT (0.47) | LMNAMAPTALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303826-B1 | SUBSTITUTED 2-NITRO METAPHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING KERATINOUS FIBRES AND ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1991-02-27 | — | — | EP | disclosed |
| US-4863482-A | FROM A TRIHALONITROBENZENE | L'OREAL (FR) | 1989-09-05 | — | — | US | disclosed |
| EP-0303826-A1 | Substituted 2-nitro metaphenylene diamines, process for their preparation and their use in dyeing keratinous fibres and especially human hair | L'OREAL (FR) | 1989-02-22 | — | — | EP | disclosed |