Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31569072 | 0.89 | MAPT (0.45) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL20500421 | 0.89 | MAPT (0.45) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL2846073 | 0.89 | HTT (0.50) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL11745815 | 0.87 | ALDH1A1 (0.46) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL1116033 | 0.83 | PKM (0.54) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL1437052 | 0.82 | CYP1A2 (0.46) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL1116017 | 0.82 | KDM4E (0.45) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL15019155 | 0.81 | MAPT (0.40) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL971178 | 0.79 | GRIN2D (0.44) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL11377025 | 0.79 | MAPT (0.68) | MAPTKDM4EMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303826-B1 | SUBSTITUTED 2-NITRO METAPHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING KERATINOUS FIBRES AND ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1991-02-27 | — | — | EP | claimed |
| US-4863482-A | FROM A TRIHALONITROBENZENE | L'OREAL (FR) | 1989-09-05 | — | — | US | claimed |
| EP-0303826-A1 | Substituted 2-nitro metaphenylene diamines, process for their preparation and their use in dyeing keratinous fibres and especially human hair | L'OREAL (FR) | 1989-02-22 | — | — | EP | claimed |
| EP-0303826-B1 | SUBSTITUTED 2-NITRO METAPHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING KERATINOUS FIBRES AND ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1991-02-27 | — | — | EP | disclosed |
| US-4863482-A | FROM A TRIHALONITROBENZENE | L'OREAL (FR) | 1989-09-05 | — | — | US | disclosed |
| EP-0303826-A1 | Substituted 2-nitro metaphenylene diamines, process for their preparation and their use in dyeing keratinous fibres and especially human hair | L'OREAL (FR) | 1989-02-22 | — | — | EP | disclosed |